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Effects of PROeq™ Postbiotic in YoungHorses: Part 2 - LPS Challenge

Horses fed the diet with PROeq™ postbiotic responded more rapidly and demonstrated a higher overall CPII (cartilage synthesis):C2C (cartilage degradation) ratio versus control horses. This suggests that they were able to balance the acute inflammatory insult to the joint with consistent, insult-appropriate levels of cartilage breakdown and synthesis until the response was no longer needed and these functions returned to baseline. In contrast, the responses of control horses appeared to be more erratic and less efficient.


LPS Joint Challenge
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